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|
Characteristic
|
Healthy control (HC)
|
Ulcerative colitis (UC)
|
Crohn’s disease (CD)
|
|---|
|
n
|
27
|
14
|
10
|
|
Male/female
|
11/16
|
7/7
|
3/7
|
|
Age at sampling
|
51 (20-77)
|
47.3 (24-70)
|
47.2 (21-77)
|
|
Inflammation categories
|
|
None
| |
4
|
4
|
|
Mayo 1 (mild disease)
| |
5
|
3
|
|
Mayo 2 (moderate disease)
| |
5
|
1
|
|
Mayo 3 (severe disease)
| |
0
|
1
|
|
Perianal disease
| |
0
|
0
|
|
Chronic obstruction
| |
0
|
0
|
|
Terminal ileum resection
| |
0
|
1
|
|
IBD medications at sampling
|
|
None
| |
8
|
5
|
|
Aminosalicylates
| |
5
|
3
|
|
Azathioprine/6-mercaptopurine
| |
1
|
3
|
|
Buscopan
| |
0
|
1
|
|
Non-IBD medications at sampling
|
|
Ondansetron
| |
0
|
1
|
|
None
| |
14
|
9
|
- Demographic and clinical data analysed in Figs. 1, 2, 3, 4 and 5 and Supplementary Figs 1-4
